Chlorhexidine allergy. 2, 3 The cases presented in The U.
Chlorhexidine allergy was post hoc defined as a relevant clinical reaction to chlorhexidine combined with two or more positive tests. Low concentration products sold over-the-counter do not typically cause serious problems, but people can have adverse effects and allergic reactions even with normal use. 17 The absence of mandatory Jun 8, 2023 · Chlorhexidine and allergic reactions: While chlorhexidine is generally safe for dogs, some dogs might experience an allergic reaction after using it. The code is exempt from present on admission (POA) reporting for inpatient Jun 24, 2014 · Chlorhexidine allergy was post hoc defined as a relevant clinical reaction to chlorhexidine combined with two or more positive tests. Purpose of ReviewIn recent years, the risk of allergy to chlorhexidine is increasingly recognised. Chlorhexidine gluconate side effects. In total, 22 of 228 patients (9. In an article titled, “Chlorhexidine: Uses and Adverse Reactions” from the journal Dermatitis, the authors present data indicating that the reports of chlorhexidine allergy are increasing. Despite its superior antimicrobial properties, chlorhexidine is a potentially allergenic substance. As use has become widespread, increasing numbers of cases of allergy have been reported in the literature, including cases of anaphylaxis to chlorhexidine gels Aug 14, 2020 · Chlorhexidine is a topical antiseptic that is generally well tolerated in patients, making it a common preparatory substance in various surgical settings. . ChloraPrep One-Step may cause serious side effects. Conclusion: This study confirms that chlorhexidine allergy is IgE-mediated and that measurement of specific IgE and histamine release are good adjuncts to skin testing in patients with clinical history suggesting chlorhexidine allergy. Iodine as an antigen or component of radiocontrast dyes If there is any suspicion of immediate allergy to chlorhexidine, prick-tests or even intradermal reaction (IDR) techniques are highly recommended. Apr 24, 2022 · For those rare patients with true allergy to PI, 0. Jun 28, 2022 · Allergic reactions, while rare, are a serious risk. 3 Patch testing has demonstrated a positive reaction in 0. Although allergic reactions to chlorhexidine digluconate are uncommon, researchers found that more than half of these reactions were clinically relevant. These side effects may go away during treatment as your body adjusts to the medicine. If we damage this, the healing phase takes longer, and the likelihood of a favourable outcome with therapy is low. Apr 27, 2016 · Chlorhexidine (CHX) is a synthetic biguanide available in different forms (diacetate, dihydrochloride, and digluconate) and used as an antiseptic. Jul 11, 2022 · Background: Chlorhexidine is an antiseptic widely used in healthcare settings. 22-μm filter, and aseptically dispensing it into May 26, 2020 · The only absolute contraindication to CHG mouthrinse use is hypersensitivity to CHG or to any components found in the product formulation. Results. Recent findings: Numerous reports have been published from many different specialties. Use a clean washcloth to wash your skin with the CHG soap. The code is valid during the current fiscal year for the submission of HIPAA-covered transactions from October 01, 2023 through September 30, 2024. Background: Chlorhexidine (CHX) is a widely utilized disinfectant that can cause IgE-mediated urticaria/anaphylaxis. May 29, 2023 · Chlorhexidine may cause a severe allergic reaction. 9, osmolality 270 mOsmol/kg) under a laminar flow hood, filtering the solution through a 0. It can reduce the inflammation, swelling, and bleeding of gingivitis. 5 Dec 15, 2014 · A cluster of anaphylactic reactions due to central lines in Japan prompted a withdrawal of chlorhexidine from in 1990s and a FDA alert in 1998 . Also, your health care professional may be able Jun 13, 2007 · Allergy to latex is thoroughly described in the literature, but allergy to chlorhexidine is less well known. com Chlorhexidine allergy is a well recognised cause of anaphylaxis during surgery. Apr 1, 2015 · Chlorhexidine has been widely reported to cause IgE-mediated allergic reactions (from urticaria and angioedema to anaphylaxis) among patients undergoing surgery/invasive procedures. The majority were life‐threatening. Rather, it enables the Government to take risk management actions Chlorhexidine allergy is a well recognised cause of anaphylaxis during surgery. This allergy is usually unrelated to eczema rashes (delayed allergy). It is widely used as an antiseptic and disinfectant and not only in the occupational environment as it is present in toothpaste, mouthwash, nose and eye drops and ointments. In both cases chlorhexidine was used after tooth extraction to disinfect the socket, and exposure to the open wound was a suspected aggravating factor. May 9, 2014 · Allergic reactions to chlorhexidine are relatively rare, particularly when one considers how widespread the use of the substance is in our living environment. Policies and procedures will reflect variations in practice Aug 7, 2022 · In the cases in which patients died, both had open wounds and the uptake of the active ingredient was too high, inducing severe allergic reactions. The Guideline for Preoperative Patient Skin Antisepsis was approved by the AORN Guidelines Advisory Board and became effective as of May 13, 2021. The cross-reactivity of patients with IgE-mediated CHX allergy with other disinfectants, which share structural similarities with CHX like polyhexanide (polyhexamethylene biguanide; PHMB), alexidine (ALX), or octenidine (OCT), is unknown. Pat yourself dry with a clean, soft towel. Rare. Use is contraindicated in patients with a history of allergy to chlorhexidine. Rinse 2 times a day, in the morning and in the evening. Recently, it was found that both skin prick testing Apr 26, 2024 · Signs of allergic reaction (nasal congestion; shortness of breath or troubled breathing; skin rash, hives, or itching; or swelling of face Other side effects Some side effects of chlorhexidine topical may occur that usually do not need medical attention . Chlorhexidine destroys the bacteria, thereby preventing the Aug 11, 2023 · Chlorhexidine gluconate solution, 4%. One report suggests that over 9% of perianesthetic anaphylaxis may be related to chlorhexidine sensitivity (Opstrup). Chlorhexidine is also used to clean the hands before a procedure. Based on this definition, sensitivity and specificity were estimated for each test. We report 2 recent cases of patients suffering significant allergic reactions to ChloraPrepTM complicating routine foot and ankle surgery. Anaphylaxis to chlorhexidine has been increasingly reported throughout the world, including two incidents in the UK where chlorhexidine-containing mouthwash had been used to wash tooth sockets following recent tooth Chlorhexidine is an antiseptic and disinfectant used against bacteria, viruses and fungi. Chlorhexidine skin treatments can be used by adults and children. Symptoms may include wheezing, rash, facial swelling, and anaphylactic shock. Feb 6, 2024 · This guide explores common paw problems like allergies, infections, and hot spots in dogs. Consequently, it has become an ubiquitous antiseptic in healthcare and the community. 1 Hypersensitivity reactions to CHX are increasingly reported and include allergic contact dermatitis, photosensitivity, fixed Chlorhexidine allergy is a well recognised cause of anaphylaxis during surgery. Apr 8, 2024 · If you have an allergy to chlorhexidine gluconate or any other part of chlorhexidine gluconate (topical). Nov 15, 2018 · Chlorhexidine-based skin preparations are frequently used in orthopaedic surgery. 2, 3 The cases presented in The U. To make sure chlorhexidine is safe for you, tell a pharmacist or doctor before using it if you: have ever had an allergic reaction to chlorhexidine or any of the other ingredients; have ever had an allergic reaction to any other medicine; cannot drink or need to avoid alcohol. This narrative review summarises the current pub-lished knowledge on chlorhexidine allergy in the perioperative setting, as it has become one of the most Chlorhexidine is an antiseptic with a broad spectrum of activity and a persistent effect on skin. (1) Allergic reactions are reported with increasing Nov 9, 2023 · Chlorhexidine mouthwash is a prescription mouthwash that decreases bacteria in your mouth. It helps prevent skin infections by killing germs; it doesn't treat skin infections that you already have. It is recommended to perform a patch test before using Chlorhexidine-containing products on a large area of the skin. Multivarious hypersensitivity reactions to the agent have been reported, including delayed hypersensitivity reactions such as co … Chlorhexidine allergy is a well recognised cause of anaphylaxis during surgery. Allergic reactions to chlorhexidine are rare, but are increasing in frequency Chlorhexidine allergy - Australasian Society of Clinical Immunology and Allergy (ASCIA) Apply alcoholic chlorhexidine, with a chlorhexidine concentration greater than 0. Uses. Severe allergic reactions including anaphylaxis have been reported following use of chlorhexidine. Tell your doctor about the allergy and what signs you had. If a patient experiences a reaction possibly related to CHG product, contact the patient’s treating physician for all clinical decisions on whether to stop the product or provide any medication to address a possible reaction. Descriptions. Nevertheless, cases of contact allergies or even type-1 allergies are consistently reported in the literature [3, 4]. Other topical antiseptics, notably chlorhexidine, have also been associated with systemic reactions, particularly when applied to disrupted or injured epithelial surfaces. Number of records containing chlorhexidine and associated hypersensitivity reactions, by year. Jun 29, 2019 · The proposed order adding chlorhexidine and its salts to Schedule 1 to CEPA 1999, also called the List of Toxic Substances, was published for a 60-day public comment period ending on May 5, 2021. Learn how to identify paw issues, use chlorhexidine safely, and keep your pup's paws happy and healthy. Allergy to chlorhexidine has been increasingly reported particularly in the perioperative and medical procedural settings. 1 These may present as burning mouth in mild cases, but more serious reactions can be life-threatening. The prevalence of chlorhexidine Chlorhexidine belongs to a group of medicines called antiseptic antibacterial agents. 13–15 A recent survey from 13 centers reported 252 cases of anaphylaxis to chlorhexidine, and it was Sep 12, 2022 · Chlorhexidine damaged the fibroblasts, which are essential factors in reattachment. Chlorhexidine (1:6-di-4’-chlorophenyldiguanidohexane) is a synthetic biguanide, broad-spectrum antiseptic and disinfec-tant used widely in the healthcare sector in many countries. 3 It has not proven possible to definitively determine the incidence of chlorhexidine-induced anaphylaxis for multiple reasons. Testing for chlorhexidine allergy is based on skin testing and in vitro testing. Chlorhexidine hypersensitivity seems to be more frequent than initially estimated and an increasing attention is dedicated to this disinfectant as potential allergen, complicating general anesthesia, despite the fact that the real incidence of immediate-type adverse reactions is still unknown and underestimated. Chlorhexidine allergy has recently been increasingly reported particularly in the perioperative and medical procedural settings. Follow the picture below. The recommendations in the guideline are intended to be achievable and represent what is believed to be an optimal level of practice. The hypersensitivity reactions range from mild cutaneous reactions to anaphylaxis or death. surgical hand scrub: significantly reduces the number of microorganisms on the hands and forearms prior to surgery or patient care - healthcare personnel handwash: handwash to help reduce Oct 22, 2018 · Women who had known allergy to chlorhexidine, alcohol, iodine, or shellfish, or who had a skin infection adjacent to the operative site were excluded. Get emergency medical help if you have signs of an allergic reaction: hives, severe skin rash; wheezing, difficult breathing; cold sweats, severe dizziness; swelling of your face, lips, tongue, or throat. Symptoms range from mild skin symptoms to life-threatening anaphylaxis. Very rarely, people can have an rapid onset serious allergic reaction (immediate allergy) to chlorhexidine. Jun 3, 2021 · In this review, we analyzed all case reports published between the introduction of chlorhexidine and the end of 2019 for allergic responses associated with the use of medical devices and or other medical products containing chlorhexidine (CHX) to ascertain the prevalence of severe CHX allergic reactions and what practices might best mitigate Feb 13, 2019 · These allergy reports and inclusion of the antiseptic in a large number of products in the healthcare environment have led to the description of chlorhexidine as ‘the hidden allergen’. However, it is important to note that some dogs may be allergic to chlorhexidine, and it may cause skin irritation or dryness. Jul 18, 2023 · July 18, 2023. Hypersensitivity reactions: Irritation, sensitization, and generalized allergic reactions have been reported with chlorhexidine-containing products, especially in the genital areas. Delayed minor allergic reaction may be overlooked or erroneously ascribed to other agents. Generic Name Chlorhexidine DrugBank Accession Number DB00878 Background. Allergic reactions. Use clean sheets on your bed after your CHG shower. Many chlorhexidine-based products are used during the perioperative period, for example lubricating gel for urethral catheterisation; skin cleaning solutions; and anti-bacterial wipes Aug 14, 2020 · The true incidence of allergy to chlorhexidine remains unknown and may be underreported. Chlorhexidine is a broad-spectrum antimicrobial biguanide used as a topical antiseptic and in dental practice for the treatment of inflammatory dental conditions caused by microorganisms. Many health professionals are unaware of its presence in different products, so it is often a ‘hidden’ allergen. Less than 1% of patients patch-tested to the topical antiseptic chlorhexidine digluconate 1% aqueous had an allergic reaction, with approximately half of the reactions Oct 5, 2020 · Whilst latex allergy has decreased, widespread use of another environmental allergen, chlorhexidine, has led to a dramatic rise in the number of severe allergic reactions to this agent. 1 Epidermal chlorhexidine preparations have produced a gradient of adverse reactions ranging from mild hypersensitivity to severe anaphylaxis. Some side effects may occur that usually do not need medical attention. Compared to its ubiquitous use in medical and non-medical environments, the sensitization rate seems to be low. A total of 50 cases were reported in a 2004 literature review . It works by killing or preventing the growth of bacteria on the skin. Use enough CHG soap to cover the skin on your entire body from the jaw down. 5% in alcohol. In countries adopting this practice, chlorhexidine allergy is generally commonly identified. The Aug 14, 2020 · Chlorhexidine is an antiseptic commonly used to prepare skin and mucous membranes for surgical procedures. MHRA/CHM advice: Chlorhexidine solutions: reminder of the risk of chemical burns in premature infants (November 2014) With topical use: In premature infants, use sparingly, monitor for skin reactions, and do not allow solution to pool—risk of severe chemical burns. Allow the antiseptic solution to dry before placing the catheter. Data was collected by searching Web of Science records published in all languages from 1965–present, accessed on January 3, 2013, for chlorhexidine and the keywords contact allergic dermatitis or allergic contact dermatitis or contact allergy or delayed hypersensitivity or urticaria or anaphylaxis Dec 11, 2014 · Healthcare professionals are reminded that chlorhexidine is known to induce hypersensitivity, including generalised allergic reactions and anaphylactic shock. 24%–2% of individuals, 6,7 with an even higher incidence in patients with a history of atopic dermatitis, leg ulcers, and leg eczema. 7 In 1984, the first case of chlorhexidine induced anaphylaxis in the perioperative setting was reported in a 9-year-old Japanese boy. As its use increases secondary to a generally favorable toxicity profile, reports of adverse reactions are increasing. Recently, it was found that both skin prick testing and specific IgE have high sensitivities and specificities Apr 3, 2024 · Brush and floss your teeth before rinsing. A history of other allergies, such as eczema, asthma, or allergic rhinitis (hay fever), does not appear to increase the risk of having chlorhexidine allergy. 4 Most reported allergic reactions occurred during the perioperative period of medical surgeries in hospital settings, and were primarily attributed to exposure to chlorhexidine as a surface disinfectant. Chlorhexidine allergy has recently been increasingly reported Feb 24, 2022 · The RDH who wrote that tell-all chlorhexidine article actually works for OraCare, which uses chlorine dioxide (ClO 2) as an alternative. Although rare, the number of reports of serious allergic reactions to these products has increased over the last several years. See full list on link. Chlorhexidine gluconate can cause a rare but serious allergic reaction that may be life-threatening. Chlorhexidine allergy is a well recognised cause of anaphylaxis during surgery. Clinical implications: IgE and histamine release can be used to support the diagnosis of allergy to chlorhexidine. In this article we report a life-threatening anaphylactic shock with Jun 6, 2023 · In conclusion, chlorhexidine is an effective treatment for various skin conditions in dogs such as hot-spots, ear infections, and fungal infections. 11 It is one of the most common skin and mucous membrane antiseptic agents in use today. 02% aqueous chlorhexidine can be used on the eye . Chlorhexidine is an antiseptic agent, commonly used, in many different preparations, and for multiple purposes. Health Canada’s safety review determined that topical chlorhexidine may cause serious allergic anaphylactic reactions in certain conditions when used in the mouth, on open wounds, or immediately before or during surgery. Discover how chlorhexidine, a gentle antiseptic, can soothe irritated paws, promote healing, and even prevent future problems. 1). Men undergoing urological or cardiothoracic surgery predominated. Interventions: 1147 women were randomly assigned to receive preoperative skin preparation with either chlorhexidine–alcohol (N = 572 women) or iodine–alcohol (N = 575). Aug 1, 2019 · Chlorhexidine is a commonly used antiseptic and disinfectant in the health-care setting. Purposes. Chlorhexidine digluconate is a disinfectant widely used in patients' homes and during contact with health services in Denmark and other countries. Q 4: Can chlorhexidine cause dermatitis? Chlorhexidine can cause irritant dermatitis. There are increasing reports of significant hypersensitivity reactions associated with its use. If you are allergic to chlorhexidine gluconate (topical); any part of chlorhexidine gluconate (topical); or any other drugs, foods, or substances. It is used to clean the skin after an injury, before surgery, or before an injection. Surgical hand scrub - Healthcare personnel handwash - Skin wound and general skin cleanser. If adverse reactions occur and last more than 72 hr, discontinue use immediately and, if severe, contact a health care provider. 9–12 The prevalence of perioperative allergic reactions was 9–10% in the United Kingdom, Denmark, and Belgium. Importantly, CHX inhibits fibroblasts, 4 and a new study notes issues with antimicrobial resistance, where the rinse itself becomes less effective and cross-resistant to other forms of Chlorhexidine allergy is a well recognised cause of anaphylaxis during surgery. Jan 7, 2010 · Exclusion criteria were a history of allergy to chlorhexidine, alcohol, or iodophors; evidence of infection at or adjacent to the operative site; and the perceived inability to follow the patient Signs of allergic reaction (nasal congestion; shortness of breath or troubled breathing; skin rash, hives, or itching; or swelling of face. Epidemiologic data suggest that the cases of chlorhexidine allergy appears to be increasing. We advise vigilance for this possible issue and recommend thorough removal of all preparation at the end of the procedure. Chlorhexidine has antibacterial properties and its use has increased dramatically over time with a parallel increase in the number of allergic reactions to it. 2 The molecule itself is a cationic bis Mar 14, 2019 · This review discusses why the allergy is so easily overlooked and point out several preventative initiatives that can minimise the risk of both chlorhexidine sensitisation and allergy development and accidental re-exposure in patients with chlor hexidine allergy. Chlorhexidine can cause a rare but serious allergic reaction that may be life-threatening. Apr 15, 2024 · If you are allergic to Peridex (chlorhexidine gluconate (oral)); any part of Peridex (chlorhexidine gluconate (oral)); or any other drugs, foods, or substances. Frankly, chlorhexidine is destroying the healing process. This medicine may interact with other drugs or health problems. Food and Drug Administration (FDA) is warning that rare but serious allergic reactions have been reported with the widely used skin antiseptic products containing chlorhexidine gluconate. In the past few years, there has been a substantial increase in the number of CHX-containing products used in health care. This can be prepared by diluting a 20% chlorhexidine digluconate solution with acetate buffer (pH 5. Allergic reactions to chlorhexidine. 1 Reattachment is the entire purpose of scaling and root planing. Apr 5, 2019 · Chlorhexidine is an antiseptic with a broad spectrum of activity and a persistent effect on skin. May 1, 2014 · Testing for chlorhexidine allergy is based on skin testing and in vitro testing. Nevertheless, cases of contact allergies or even type-1 allergies are consistently reported in the literature [ 3 , 4 ]. The patient’s age ranged from 22 to 79 years. The following is a review of the current evidence-based knowledge of allergic reactions to chlorhexidine associated with surgical and Mar 14, 2019 · Testing for chlorhexidine allergy is also discussed. In the event of confirmed allergy to chlorhexidine, strict eviction is required, bearing in mind that over a hundred medicinal products currently on the French market contain chlorhexidine. Allergic reactions to Chlorhexidine, such as skin rashes or itching, are rare but can occur. Signs of allergic reaction (nasal congestion; shortness of breath or troubled breathing; skin rash, hives, or itching; or swelling of face. 3 is a billable diagnosis code used to specify a medical diagnosis of allergy status to other anti-infective agents. Based on this definition, sensitivity and specificity were Chlorhexidine allergy is a well recognised cause of anaphylaxis during surgery. In some cases, Chlorhexidine has been associated with contact dermatitis or mucosal irritation. Development of chlorhexidine allergy has been identified as an important occupational risk to healthcare workers (HCWs). Z88. Dec 21, 2023 · Chlorhexidine topical side effects. Chlorhexidine is an antibacterial agent that is commonly used in dental and surgical settings. In the NAP6 study in the UK, chlorhexidine was the causal agent in 9% of life-threatening perioperative allergic reactions. We describe an observational survey of diagnostic pathways in 104 patients attending four specialist allergy clinics in the United Kingdom following perioperative hypersensitivity reactions to chlorhexidine reactions. Do not swallow chlorhexidine gluconate (oral). Do not eat, brush teeth, or rinse with water or other mouthwash right after using chlorhexidine gluconate (oral). The Centre for Adverse Reaction Monitoring (CARM) has received eight reports of anaphylactic reactions to chlorhexidine and lignocaine combination products in men undergoing urinary catheterisation. Apr 17, 2013 · Chlorhexidine is a low molecular weight occupational sensitizer that can cause different delayed and immediate-type allergic reactions including anaphylaxis. Anaphylaxis to chlorhexidine is a rare but potentially life-threatening complication. Get emergency medical help if you have any of these signs of an allergic reaction: hives, severe skin rash; wheezing, difficult breathing; cold sweats, feeling light-headed; swelling of your face, lips, tongue, or throat. As use has become widespread, increasing numbers of cases of allergy have been reported in the literature, including cases of anaphylaxis to chlorhexidine gels used on mucous membranes, chlorhexidine-impregnated Chlorhexidine allergy is a well recognised cause of anaphylaxis during surgery. Rinse your body well. If there is a contraindication to chlorhexidine, apply tincture of iodine, an iodophor, or alcohol as an alternative. It helps to reduce the inflammation (redness) and swelling of your gums and to reduce gum bleeding. Several hypersensitivity reactions due to chlorhexidine have been described. Hibiclens (chlorhexidine) is available as solutions (soaps), gels, and cloths that are used on the skin of adults and children Chlorhexidine is a highly effective antiseptic agent. Gingivitis is caused by the bacteria that grow in the coating (plaque) that forms on your teeth between tooth brushings. Sparse case reports have identified immediate hypersensitivity reactions after exposure to this substance, especially in patients with a history of atopy. Povidone-iodine in individuals known to be allergic to iodine or product ingredients is contraindicated. 6%) met the definition of allergy to chlorhexidine. S. 8 The true prevalence of chlorhexidine allergy is still unknown and is thought to be under-recognized. Rinse with 1 tablespoon (15 mL) of chlorhexidine gluconate (oral) for 30 seconds. Chlorhexidine is used to treat gingivitis. In some cases, a dog might develop an allergic reaction to chlorhexidine after repeated exposure. 5 An alternative Many dental professionals feel “the bad” and “the ugly” of chlorhexidine outweigh “the good,” leaving them in search of an alternative. Sep 3, 2014 · Despite this recommendation, chlorhexidine is commonly used in neonatal intensive care units in the USA, mostly for skin preparation and maintenance for central venous access 41. If you’re Mar 9, 2020 · Chlorhexidine is a synthetic bisbiguanide antiseptic and was introduced in healthcare use in 1954. Jul 8, 2017 · Chlorhexidine is an effective antiseptic which is widely used in dentistry. [20] A 2019 Cochrane review concluded that based on very low certainty Sep 25, 2023 · Hibiclens (chlorhexidine gluconate) is an over-the-counter, antiseptic product that's used to clean the skin. springer. Plus, there is no bad taste. Common signs of an allergic reaction include itching, hives, and swelling. 7–9 These individuals, in addition to those previously May 13, 2018 · As exposure to chlorhexidine is highly likely in any surgical setting, several centres routinely test all patients referred with perioperative anaphylaxis for chlorhexidine allergy. May 13, 2016 · Serious allergic anaphylactic reactions to non-prescription topical chlorhexidine products are not common. Chlorhexidine is used in disinfectants (disinfection of the skin and hands), cosmetics (additive to creams, toothpaste, deodorants, and antiperspirants), and pharmaceutical products (preservative in eye drops, active substance in wound dressings and antiseptic mouthwashes). In this review, we discuss why ing chlorhexidine on her forearms. Adding a substance to the list does not restrict its use, manufacture or import. At only 44 milligrams per liter, OraCare’s chlorine dioxide wash requires a much lower concentration of its active ingredient. (Fig. This means that you should avoid putting products containing chlorhexidine onto your skin in the future. Hypersensitivity reactions to chlorhexidine include delayed and immediate type allergies. Chlorhexidine • Allergic reactions are rare, but can occur. Chlorhexidine is a widely used antiseptic and disinfectant. Over recent years, it has also been used in other healthcare products as well as in cosmetics. xu ae ta ix kr ty np vu no gu
